Bubbles, foam and gush

by Vivienne Baillie Gerritsen

A ting of metal against glass. The lights are dimmed. Voices turn to a murmur. All eyes are set on the bottle of champagne and its cork as it is gradually eased out. Then a pop, and your host is nervously juggling with glasses and a challenging flow of bubbles. These are bubbles we expect. However, sometimes bubbles emerge in an uncontrollable gush. Take a can of beer; one that has been waiting patiently in the fridge. It hasn't been shaken. It hasn't fallen. The can itself is pristine. You slip a finger under the tab and pull. You expect some foam but not the untamed rush of bubbles that spills over your hands and onto the ground. When it finally ends and you peer into the can, there's little left to drink. Gushing such as this is a defect which occurs in carbonate beverages. At the beginning of the 20th century, scientists speculated that something biological was probably the culprit, but they were unable to put their finger on it. Today, researchers postulate that gushing is most likely caused by hydrophobins. Hydrophobins are proteins synthesized by fungi that have infected the grain used in the production of beer. In particular, class II hydrophobin 5 from Fusarium culmorum.

Protein Spotlight (ISSN 1424-4721) is a monthly review written by the Swiss-Prot team of the SIB Swiss Institute of Bioinformatics. Spotlight articles describe a specific protein or family of proteins on an informal tone. Follow us: Subscribe · Facebook · Linkedin

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LIFE, LOVE, DEATH & PROTEINS

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"La vie, l'amour, la mort & les protéines" (in French only) is a wonderful and unique collection of twenty comic strips created with cartoonist aloys lolo. Each comic describes one protein taken from the Protein Spotlight articles. The album was published in November 2023 by Antipodes, Switzerland. Order your copy online. English version online here.

Snapshot : Titin

Senora Pilasana
Voulez-vous le taximeter?
Le tionta su la seata
Tu la tu la tu la wa
This is gibberish sung by Charlie Chaplin in ‘Modern Times’ as he struggles to satisfy an impatient audience whilst frantically seeking for his cuff – on which he had written the true lyrics – which had flown off his wrist following an unfortunate flick as he made a hasty entry to perform. He ad-libs novel lyrics to the tune of ‘Je cherche après Titine’ (‘Looking for Titine’) a then popular French song written by M.Bertal and L.Maubon in 1917, the music of which was composed by L.Daniderff. As a result, Chaplin not only added to the song’s popularity but also made it worldwide. Little did he know though that what helped him to dash around the dining-room as he searched for the lost cuff is also named…titin….

A little bit of praise!

“I recently stumbled upon your columns. Let me congratulate you on achieving the near impossible, for your articles have enabled me to successfully marry IT with the Life Sciences and better explain the concepts of bioinformatics to those who are not in the know of the field.

Your articles are very well written, lucid, and contain just enough information to excite the reader to want to learn more about the topic being discussed. They fall in a very rare category where they are accessible to everyone, from the undergraduate students to research students who want to have a basic idea of the topics being discussed. Some of your articles, like "Our hollow architecture" and "Throb" are outstanding pieces.

I would highly recommend your articles as a necessary reading in undergrad classes to get students inspired about the various avenues of research.”

— Rohan Chaubal, Senior Researcher in Genomics

Thank you to Leonardo da Vinci whose work we reproduce on our site!